Diets low in processed foods may double weight loss @ יואל קסלר .קום

בפוסט הזה ביואל קסלר.קום, מחקר חדש שפורסם מציע כי תזונה דלת מזונות מעובדים או מעובדים במיוחד עשויה להכפיל את הירידה במשקל.

A new study published in Nature Medicine suggests that a diet that is low in processed or ultra processed foods may double weight loss. A copy of the abstract is reprinted below. The full article can be found here.

Ultraprocessed or minimally processed diets following healthy dietary guidelines on weight and cardiometabolic health: a randomized, crossover trial

• Samuel J. Dicken, 
• Friedrich C. Jassil, 
• Adrian Brown, 
• Monika Kalis, 
• Chloe Stanley, 
• Chaniqua Ranson, 
• Tapiwa Ruwona, 
• Sulmaaz Qamar, 
• Caroline Buck, 
• Ritwika Mallik, 
• Nausheen Hamid, 
• Jonathan M. Bird, 
• Alanna Brown, 
• Benjamin Norton, 
• Claudia A. M. Gandini Wheeler-Kingshott, 
• Mark Hamer, 
• Chris van Tulleken, 
• Kevin D. Hall, 
• Abigail Fisher, 
• Janine Makaronidis & 
• Rachel L. Batterham 

Abstract

Ultraprocessed food (UPF) consumption is associated with noncommunicable disease risk, yet no trial has assessed its health impact within the context of national dietary guidelines. In a 2 × 2 crossover randomized controlled feeding trial, 55 adults in England (body mass index ≥25 to <40 kg m⁻², habitual UPF intake ≥50% kcal day⁻¹) were provided with two 8-week ad libitum diets following the UK Eatwell Guide: (1) minimally processed food (MPF) and (2) UPF, in a random order. Twenty-eight people were randomized to MPF then UPF, and 27 to UPF then MPF; 50 participants comprised the intention-to-treat sample. The primary outcome was the within-participant difference in percent weight change (%WC) between diets, from baseline to week 8. Participants were blinded to the primary outcome. MPF (%WC, −2.06 (95% confidence interval (CI), −2.99, −1.13) and UPF (%WC, −1.05 (95% CI, −1.98, −0.13)) resulted in weight loss, with significantly greater %WC on MPF (Δ%WC, −1.01 (95% CI, −1.87, −0.14), P = 0.024; Cohen’s d, −0.48 (95% CI, −0.91, −0.06)). Mild gastrointestinal adverse events were common on both diets. Findings indicate greater weight loss on MPF than UPF diets and needing dietary guidance on food processing in addition to existing recommendations. Clinicaltrials.gov registration: NCT05627570.

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