Background
In this post – Low vitamin D associated with migraine @ יואל קסלר .קום – A number of studies have postulated a connection between low Vit D and migraine but results have been inconsistent. In a recent publication by Hao et. al. a review of NHANES data suggested a positive association between low vit D levels and prevalence of migraine in US adults.
בפוסט זה - ויטמין די נמוך קשור למיגרנה @ יואל קסלר .קום - מספר מחקרים העלו על קשר בין דל ויטמין די למיגרנה אך התוצאות לא היו עקביות. בפרסום שנערך לאחרונה על ידי סקירת נתונים הציע קשר חיובי בין רמות נמוכות של ויטמין די ושכיחות מיגרנה בקרב מבוגרים בארה"ב.
The abstract is reprinted below. The full article can be found here.
Association between serum vitamin D and severe headache or migraine: A population-based analysis
Abstract
Background
Vitamin D is thought to play a role in the development of migraine, but the nature of the relationship is still not fully understood. Although some studies have shown an association between vitamin D deficiency and migraine, other studies have had inconsistent or inconclusive results. Therefore, further research is needed to better understand the relationship between vitamin D and migraine headaches.
Methods
We selected 9142 participants from the 2001–2004 National Health and Nutrition Examination Survey (NHANES). In our study, the term "serum vitamin D" refers to the concentration of 25OHD2 + 25OHD3 (nmol/L) in the blood. Migraine was assessed based on self-reports in the miscellaneous pain section of the NHANES questionnaire. Associations between vitamin D and the risk of migraine were examined using multiple logistic regression, smoothed curve fitting, and stratified analyses.
Results
In our study, 20.53% of the participants suffered from migraine. The prevalence of migraine was higher in those with lower serum vitamin D levels. Participants in the highest quartile of serum vitamin D levels were found to have a 16% lower prevalence than those in the lowest quartile in the fully adjusted model (OR = 0.84, 95% CI 0.71–0.99). This result was supported by stratified analysis and smoothed curve fitting.
Conclusion
Our study showed a significant negative correlation between serum vitamin D levels and the prevalence of migraine in American adults.
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